ea0013p126 | Growth and development | SFEBES2007
Bowl Michael
, Mirczuk Samantha
, Southam Lorraine
, Mughal Zulf
, Ryan Fiona
, Shaw Nick
, Tham Elaine
, Hochberg Zeev
, Tiosano Dov
, Loughlin John
, Andrew Nesbit M
, Thakker Rajesh
GCMB, which is the mammalian homologue of the Drosophila gene Glial cells missing, encodes a 506 amino acid parathyroid-specific transcription factor that contains: a DNA-binding domain at residues 21174; a predicted nuclear localization signal at residues 176193; an inhibitory domain at residues 258347; and two transactivation domains at residues 174263, and residues 428506. Mutations of GCMB, which is located on chrom...